The United States Supreme Court has held that a live, human-made, genetically engineered microorganism is patentable subject matter under 35 U.S.C. § 101.
Diamond v. Chakrabarty, 100 S. Ct. 2204 (1980).
Ronald M. Benrey,
Patents - Statutory Interpretation - Patentability of Living Microorganisms,
Duq. L. Rev.
Available at: https://dsc.duq.edu/dlr/vol19/iss2/7