Defense Date

4-1-2021

Graduation Date

Spring 5-6-2021

Availability

One-year Embargo

Submission Type

dissertation

Degree Name

PhD

Department

Health Care Ethics

School

McAnulty College and Graduate School of Liberal Arts

Committee Chair

Joris Gielen

Committee Member

Gerard Magill

Committee Member

Peter Ikechukwu Osuji

Keywords

Ethics, Genetic Editing, CRISPR, Genetic Therapy, Transhumanism

Abstract

There are many steps involved in the process of introducing CRISPR-Cas9 into the current health care system. This dissertation provides an ethical foundation for the uses of CRISPR-Cas9 genetic therapies and editing techniques, which organizations can utilize when implementing these new technologies. Multiple components must be examined, including the practical application of the concept of autonomy, which benefits from the inclusion of personalism and care ethics as it aims to provide a more effective method upholding the right to independent decision-making. In addition to individual considerations, population-based decisions and public health tools are explored, connecting the human right to health care with the challenges that are experienced in implementing an expensive treatment. These considerations are especially important when working with vulnerable populations in research, as well as when genetic therapies are used at the beginning and end of life, when patients can be most at risk. Reflecting on how an organization currently implements new technologies as well as Pre-Implantation Genetic Diagnosis, is immensely useful and can provide further guidelines when considering genetic editing. Taking practical implications into account is crucial so that organizations can begin the process of considering their use of CRISPR-Cas9 and the education of stakeholders. The dissertation also mentions fears about future uses of genetic editing, which could allow individuals to enhance their unborn children and promote transhumanism and eugenics.

Language

English

Available for download on Saturday, May 07, 2022

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