School of Pharmacy
Caffeine, Choline, Short term memory, WRAML 2
This study sought to determine whether caffeine combined with choline could improve short-term memory in healthy adults. The study tested the effect of choline (2 gm) alone and in combination with several concentrations of caffeine (25 mg, 50mg and 100mg) on short-term verbal and visual memory and attention. The Wide Range Assessment of Memory and Learning-2 was utilized. Choline 2 gm + caffeine 25 mg group showed significantly (p<0.05) higher overall memory performance whereas memory performance in the choline 2 gm + caffeine 50 mg group was significantly impaired compared to placebo. The data suggest that specific combinations of caffeine and choline can either facilitate or impair short-term memory in adults with normal cognitive function. Future studies of caffeine and choline combinations will test memory performance in subjects with memory impairment.
Nagrecha, N. (2012). The Effect of Caffeine and Choline on Short-term Memory (Master's thesis, Duquesne University). Retrieved from https://dsc.duq.edu/etd/967