One ofthe most devastating diseases thatthreatens the world population is malaria. The 26S proteasome complex of the malaria parasite Plasmodium falciparum, which was previously unknown, was characterized by the authors through an affinity purification protocol that isolated functional 26S proteasome complexes. This allowed for the identification of subunit composition and PfUSP14, a proteasomeassociated deubiquitinase. This new understanding presents a potential target to disrupt protein regulation in thequest for effective antimalarial strategies.
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.
Grogan, C. (2017). Plasmodium falciparum 26S Proteasome Network: A Mystery Solved. D.U.Quark, 2 (1). Retrieved from https://dsc.duq.edu/duquark/vol2/iss1/6