Synthesis of 2,4-Diaminopyrido [2,3-d] pyrimidines and 2,4-Diaminoquinazolines as Inhibitors of Dihydrofolate Reductase and as Anti-tumor Agents

Defense Date

12-12-2008

Graduation Date

Spring 2009

Availability

Restricted

Submission Type

dissertation

Degree Name

PhD

Department

Medicinal Chemistry

School

School of Pharmacy

Committee Chair

Aleem Gangjee

Committee Member

Marc W. Harrold

Committee Member

Patrick T. Flaherty

Committee Member

David J. Lapinsky

Committee Member

Lawrence H. Block

Committee Member

J. Douglas Bricker

Keywords

pyridopyrimidines, quinazolines, dihydrofolate reductase inhibitors, anti-tumor agents, antifolates

Abstract

Abstract withheld

Format

PDF

Language

English

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