Author

Chad C. Brown

Defense Date

7-31-2008

Graduation Date

2008

Availability

Immediate Access

Submission Type

thesis

Degree Name

MS

Department

Computational Mathematics

School

McAnulty College and Graduate School of Liberal Arts

Committee Chair

John C. Kern

Committee Member

Frank D'Amico

Committee Member

Mark Mazur

Committee Member

Jeffrey Jackson

Keywords

urinary bladder pressure, UBP, Gibbs sampling, body mass index, repeated measures, Bayesian statistics

Abstract

Urinary bladder pressure (UBP) is an important indicator for a variety of medical conditions. Eighty hospital subjects each had their UBP measured four times at various bladder volumes and lying positions. Positions included 0 degrees supine, 30 degrees supine, 30 degrees right lateral and 30 degrees left lateral, and the volumes included 0mL, 25mL, 50mL and 200mL. For each volume, mean UBP was found to be somewhat lower for subjects measured in non-elevated position (0 degrees supine) than any of the elevated positions (30 degrees), although the sizes of the effect only sometimes reached significance. Additionally, for each position, mean UBP was found to increase as subject bladder volume increased, although the effects were only sometimes significant. Among the many demographic and medical covariates modeled, only body mass index (BMI) was found to be consistently associated with UBP. Mean UBP is expected to increase by 0.335 mmHg (P-value < 0.0001) for every unit increase in BMI, with a 95 percent confidence interval of (0.184, 0.486).

Format

PDF

Language

English

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