Pterin chemistry and its relationship to the molybdenum cofactor
DOI
10.1016/j.ccr.2011.02.010
Document Type
Journal Article
Publication Date
5-1-2011
Publication Title
Coordination Chemistry Reviews
Volume
255
Issue
2022-09-10
First Page
1016
Last Page
1038
ISSN
108545
Keywords
Biosynthesis, Chemical synthesis, Molybdenum, Pterin, Redox reaction
Abstract
The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterins and current models of the molybdenum cofactor are discussed. © 2011 Elsevier B.V.
Open Access
Green Accepted
Preprint
Repository Citation
Basu, P., & Burgmayer, S. (2011). Pterin chemistry and its relationship to the molybdenum cofactor. Coordination Chemistry Reviews, 255 (2022-09-10), 1016-1038. https://doi.org/10.1016/j.ccr.2011.02.010